冯嵬
学术任职：北京化工大学生命科学与技术学院教授
研究领域：蛋白质剪接及多酶催化
科研项目：
1. 国家自然科学基金项目，超氧阴离子自由基从黄素蛋白NrdI传递到半乳糖氧化酶(GAO)促进GAO酶活提高的机理研究。
2. 国家自然科学基金项目，纳米生物反应器内固定双酶及催化制备2,5-呋喃二甲酸的研究。
3. 国家自然科学基金项目，D-氨基酸氧化酶特异性固定及其催化研究。
4. 国家自然科学基金项目，双酶一体连续催化体系的建立及其研究。
5. 国家自然科学基金项目，碳纳米管促进有机相中脂肪酶催化的作用机理研究。
6. 国家自然科学基金项目，通过新型氢膜超临界水气化反应器转化生物质制备乙醇。
7. 863 计划，微藻色素和高值脂肪酸多联产关键技术与产品开发 多联产技术与产物综合利用。
8. 973计划，能源微藻采收、油脂提取及生物柴油制备原理与方法。
9. 国家海洋局项目，海洋微藻生物柴油规模化制备关键技术与装置的优化、耦联及应用研究
代表性学术成果：
1. Yao Chen, Jinxin Zou, Jian Sun, Qiong Qin, Peijun Ji, Wei Feng. Immobilization using Cu(II) and Zr(IV): Persistent and highly efficient activation of galactose oxidase by in-situ generation of hydroxyl radicals in concert with in-situ generation of O2. Chemical Engineering Journal, 2022, 435, 134819.
2. Jinxin Zou, Yao Chen, Wei Feng. Mechanism of DOPA radical generation and transfer in metal-free class Ie ribonucleotide reductase based on density functional theory. Computational and Structural Biotechnology Journal, 2022, 20, 1111–1131.
3. Rong Li, Yao Chen, Kun Du, Wei Feng. Peptide Bond Formation Between the Hetrosubunits of ω-Transaminase, Alanine Dehydrogenase, and FormateDehydrogenase Through Subunit Splicing Promoted by Heterodimerization of Leucine Zipper Motifs. Frontiers in Bioengineering and Biotechnology. 2020, 8, 686,1-13.
4. Jian Sun, Yaqi Fu, Rong Li, Wei Feng. Multifunctional Hollow−Shell Microspheres Derived from Cross-Linking of MnO2 Nanoneedles by Zirconium-Based Coordination Polyme: Enzyme Mimicking, Micromotors, and Protein Immobilization. Chemistry of Materials. 2018, 30, 1625−1634.
5. Rong Li, Xiaoqi Zhou, Dan Liu, Wei Feng. Enhancing the activity and stability of Mn-superoxide dismutase by one-by-one ligation to catalase. Free Radical Biology and Medicine, 2018, 129, 138-145.
6. Kun Du, Jinjin Zhao, Jian Sun, and Wei Feng. Specific Ligation of Two Multimeric Enzymes with Native Peptides and Immobilization with Controlled Molar Ratio. Bioconjugate Chemistry. 2017, 28, 1166−1175..
7. Jian Sun, Kun Du, Xiaoqiang Song, Qian Gao, Jingjing Ma, Wei Feng. Specific Immobilization of D-amino Acid Oxidase Mimicking Multi-enzyme Catalysis. Green Chemistry. 2015, 17, 4465–4472.
8. Jian Sun, Kun Du, Li Fu, Jiang Gao, Haiyang Zhang, Wei Feng. Sodium Hexadecyl Sulfate as an Interfacial Substance Adjusting the Adsorption of a Protein on Carbon Nanotubes. ACS Appl. Mater. Interfaces. 2014, 6, 15132− 15139.
9. Kun Du, Jian Sun, Xiaoqiang Song, Huaming Chen, Wei Feng, Peijun Ji. Interaction of Ionic Liquid [bmin][CF3SO3] with Lysozyme Investigated by Two-Dimensional Fourier Transform Infrared Spectroscopy. ACS Sustainable Chemistry & Engineering. 2014, 2, 1420−1428.
10. Wei Feng, Peijun Ji. Enzymes immobilized on carbon nanotubes. Biotechnology Advances. 2011, 29, 889-895.