喻长远

生命组学与大数据解读、中医药系统生物学研究、生态环境与大健康研究

发布者:刘总悦发布时间:2022-10-20浏览次数:37

喻长远

学术任职:中国中医药学会、北京市实验动物学会等委员

研究领域:生命组学与大数据解读、中医药系统生物学研究、生态环境与大健康研究

科研项目

(1) 国家自然科学基金委员会, 面上项目, 82174531, 化湿解表法对病毒侵染过程的分子靶点可视化研究, 2022-01-01 至 2025-12-31, 55万元, 在研, 主持

(2) 科技部, 重点研发计划, 2019YFC1200104, -, 2019-12 至 2022-12, 510万元, 主持

(3) 科技部, 重大专项, 2019ZX09721001-007, 重大新药创制-耐药菌防治药物品种及 共性关键技术研发, 2019-01 至 2021-06, 200万元, 结题, 主持


代表性学术成果

代表性著作:

1.Engineering High-Robustness DNA Molecular Circuits by Utilizing Nucleases, Nanoscale, 2020, DOI: 10.1039/C9NR09979D.

2.Probing DNA Hybridization Equilibrium by Cationic Conjugated Polymer for Highly Selective Detection and Imaging of Single-Nucleotide Mutation, Analytical Chemistry, 2018, 90, 6804-6810.

3.Telomerase Activity Detection with Amplification-Free Single Molecule Stochastic Binding Assay, Analytical Chemistry, 2017, 89, 3576-3582.

4.Discrimination Cascade Enabled Selective Detection of Single Nucleotide Mutation, ACS Sensors, 2017, 2, 419-425.

5.A dynamic sandwich assay on magnetic beads for selective detection of single-nucleotide mutations at room temperature, Biosensors & Bioelectronics, 2017, 94, 305-311.

6.Metabolic Profile Changes of CCl4-Liver Fibrosis and Inhibitory Effects of Jiaqi Ganxian Granule[J]. Molecules.  2016, 21(6), 698.

7.Classification Models of HCV NS3 Protease Inhibitors Based on Support Vector Machine (SVM),Combinatorial Chemistry & High Throughput Screening, 2015, 18(1), 24-32.

8.QSAR Studies on the Bioactivity of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase Inhibitors, Letters in Drug Design & Discovery, 2015, 12(9), 728-735.

9.Classification of Mixtures of Chinese Herbal Medicines Based on a Self-Organizing Map (SOM), Molecular Informatics, 2016, 35(3-4), 109-115.

10.Using support vector machine (SVM) for classification of selectivity of H1N1 neuraminidase inhibitors, Molecular Informatics, 2016, 35(3-4), 116-124.

专利:

1. 喻长远,杨昭,王璐瑶,白素杭,沈宗毅。膀胱癌耗竭型NKT细胞亚群、其特征基因及其应用。(专利申请号:202010669877.5)

2. 杨昭,王璐瑶,喻长远,白素杭,沈宗毅。膀胱癌耗竭型T细胞亚群、其特征基因及其应用。(专利申请号:202010627617 .1)

3. 喻长远,邱松,杨昭,国震宇,许立达,孙晓明,孙浩然,陈天童。一种超亲气电极提高微生物燃料电池产电量的工艺。(专利申请号:202010641473 .5)

4. 喻长远,杨昭,阎秋韵,沈宗毅,张富涵,张琨,钟博,白素杭,魏振华。一种CRISPR/Cas12a基因编辑系统及其应用。(专利申请号:201811588275.6)